Drug Standards
Apexbio Technology LLC Colchicine 64-86-8 10mM (in 1mL DMSO)
Colchicine (CAS 64-86-8) is a small-molecule inhibitor targeting tubulin polymerization It binds directly to tubulin monomers disrupting their polymerization into microtubules (IC50 3 2 M) By preventing microtubule assembly colchicine interferes with spindle formation arresting cells in mitosis at metaphase thereby functioning as a mitotic inhibitor Additionally colchicine demonstrates anti-inflammatory activity by suppressing neutrophil motility and function reducing urate crystal deposition and has been effectively used in animal models of gouty arthritis It is widely utilized in biomedical research to study microtubule dynamics mitosis control and inflammatory pathways
Medchemexpress LLC Doxycycline (hydrochloride hemiethanolate hemihydrate) | 24390-14-5 | 512.94 | 25 MG
Doxycycline hyclate is an orally active, broad-spectrum antibiotic and metalloproteinase (MMP) inhibitor. It exhibits antibacterial and anti-cancer cell proliferation activity, and can be used for constructing gene expression regulation models. It is intended for research use only.
- Affects growth of glioma cells.
- Decreases MT-CO1 protein content in SVG cells.
- Reduces proliferation of human cell lines.
- Inhibits cell viability of breast cancer cells.
- Reduces MMP-9 activity in mice.
- Used as an inducer in molecular biology for gene expression control.
Medchemexpress LLC Ruxolitinib (S enantiomer) | 941685-37-6 | 99.6% | C17H18N6 | 1 ML
Ruxolitinib (S enantiomer), also known as S-Ruxolitinib, is the S-enantiomer of Ruxolitinib. It is an orally active and potent JAK inhibitor, targeting the JAK/STAT signaling pathway. This compound is supplied as a 10 mM solution in DMSO, ready for reconstitution.
- Potent JAK inhibitor
- Orally active compound
- Suppresses IFNβ-induced gene expression in human small airway epithelial cells
- Reduces haematopoietic cell expansion in myeloproliferative neoplasms in vivo
- High solubility in DMSO (≥ 100 mg/mL)
- Recommended storage for powder at -20°C for 3 years, and in solvent at -80°C for 2 years
Medchemexpress LLC Phenol, 4,4′-(2-pyridinylmethylene)bis- | 603-41-8 | MFCD00023496 | 99.0% | 277.32 g·mol⁻¹ | C18H15NO2 | 5 MG
Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl, supplied as a solid research reagent for pharmacological and metabolic studies. It induces epithelial chloride secretion in rodent colon and rectum and is intended for use as a reference standard or analytical standard in laboratory experiments.
- High purity (99.0%) suitable for analytical and pharmacological assays.
- Defined molecular weight and formula for precise calculations.
- Available in small pack sizes for trace-level experiments.
- Supplied as a solid for stable storage and handling.
- Used as an active metabolite reference in metabolic and physiological studies.
Selleck Chemical LLC Fulvestrant 100mg 129453-61-8 ICI-182780, ZD 9238
Fulvestrant (ICI-182780, ZD 9238) is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medkoo Biosciences Inc Vemurafenib | 918504-65-1 | MFCD18074504 | 20g
Vemurafenib | Putity: > 98% | MW: 489.92 | 918504-65-1 | MFCD18074504 | 20g
Selleck Chemical LLC Ranolazine 2HCl 100mg 95635-56-6 RS-43285
Ranolazine 2HCl (RS-43285) is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Clofarabine 50mg 123318-82-1
Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Febuxostat impurity 7 | 1350352-70-3 | MFCD31807379 | 98.2% | 334.39 g/mol | C16H18N2O4S | 5 MG
Febuxostat impurity 7 is an analytical reference standard representing a synthetic impurity of febuxostat (CAS 1350352-70-3). It is intended for impurity identification, method development, and quality control applications in pharmaceutical analysis. The compound has molecular formula C16H18N2O4S and a molecular weight of 334.39 g/mol.
- High purity suitable for analytical use (≈98.2%).
- Molecular formula C16H18N2O4S and molecular weight 334.39 g/mol.
- Supplied in milligram quantities for reference standard workflows.
- Intended for impurity characterization and method development.
- Provided with product data and certificate of analysis for traceability.
Medchemexpress LLC Diphenhydramine hydrochloride | 147-24-0 | 99.9% | 100 MG
Diphenhydramine hydrochloride (Standard) is an analytical standard used for research and analytical applications. It is a first-generation histamine H1-receptor antagonist with anticholinergic effects and can cross the ovine blood-brain barrier (BBB). This standard is commonly employed in qualitative, quantitative, and methodological research experiments.
- First-generation histamine H1-receptor antagonist
- Can cross the ovine blood-brain barrier (BBB)
- Suitable for HPLC, GC, and MS research experiments
- Used in qualitative, quantitative, and methodological research
Sigma Aldrich Fine Chemicals Biosciences Furosemide Related Compound A United States Pharmacopeia (USP) Reference Standard | 4818-59-1 | MFCD18379506 | 50MG
Furosemide Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 330.74 | 4818-59-1 | MFCD18379506 | 50MG
Medchemexpress LLC Mirabegron impurity- 5g
Mirabegron impurity-1 is a potent and selective 3- adrenergic receptor agonist Mirabegron impurity-1has the activity of inhibiting metabolism Mirabegron impurity-1 can be used inthe study of the treatment of bladder impurity [1]
Cayman Chemical EnzastaurIn 25mg
A potent inhibitor of PKCβ (IC50 = 6 nM), with modest selectivity over PKCα, γ, and ε (IC50 = 39, 83, and 110 nM, respectively); at 3 µM, also inhibits signaling through the Akt pathway; suppresses angiogenesis, induces apoptosis, and reduces proliferation of cultured tumor cells
Cayman Chemical Pantoprazole 5g
A proton pump inhibitor; inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles (IC50 = 6.8 µM); reduces basal gastric acid secretion in pylorus-ligated rats (ED50 = 1.3 mg/kg); inhibits mepirizole-induced increases in gastric acid secretion in an anesthetized rat model of gastric fistula (ED50 = 0.8 mg/kg); inhibits formation of mepirizole-induced duodenal lesions in rats (ED50 = 0.5 mg/kg)
Sigma Aldrich Fine Chemicals Biosciences Cineole European Pharmacopoeia (EP) Reference Standard | 470-82-6 | MFCD00167977 |
Cineole European Pharmacopoeia (EP) Reference Standard | Mol Wt: 154.25 | 470-82-6 | MFCD00167977 |